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← The Human Genome Project's results have been less transformative than initially advertised relative to its cost.
17 connected korrents · 16 moments from 15 Jul 2021 to 22 Sept 2026.
Everything filed under AI and science
AI and science
Everything filed under mathematics
mathematics
Everything filed under protein structure prediction
protein structure prediction
Everything filed under recursive self-improvement
recursive self-improvement
Everything filed under open source
open source
Everything filed under AI alignment
AI alignment
Everything filed under LLMs
LLMs
Everything filed under AGI
AGI
Everything filed under scaling laws
scaling laws
Everything filed under Anthropic
Anthropic Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Read this korrent: The Human Genome Project's results have been less transformative than initially advertised relative to its cost. The Human Genome Project's results have been less transformative than initially advertised relative to its cost. Last stated 2 years ago
16 Feb 2025
EH
Elliot Hershberg — holds since 2025-02-16 — tap for who they are
Same subject: This work could have been run as a business; open-sourcing it simply puts the tools in more scientists' hands faster. — tap to centre the map on it This work could have been run as a business; open-sourcing it simply puts the tools in more scientists' hands faster. Last stated 4 months ago
10 Jun 2026
MZ
Mark Zuckerberg — holds since 2026-06-10 — tap for who they are
Same subject: Effective altruism's work on the far future is not a bait and switch hiding behind its work on global health; both halves are worth defending. — tap to centre the map on it Effective altruism's work on the far future is not a bait and switch hiding behind its work on global health; both halves are worth defending. Last stated 3 years ago
28 Nov 2023
SA
Scott Alexander — holds since 2023-11-28 — tap for who they are
Same subject: An AI as good as a top researcher will not be priced like one, because it competes against the other labs rather than against humans. — tap to centre the map on it An AI as good as a top researcher will not be priced like one, because it competes against the other labs rather than against humans. Last stated a year ago
15 Aug 2025
CH
Casey Handmer — holds since 2025-08-15 — tap for who they are
Same subject: A million copies of one researcher would hit diminishing returns quickly, because what research needs is people who think differently. — tap to centre the map on it A million copies of one researcher would hit diminishing returns quickly, because what research needs is people who think differently. Last stated 11 months ago
25 Nov 2025
IS
Ilya Sutskever — holds since 2025-11-25 — tap for who they are
Same subject: The last steps to AGI should be taken by a CERN-style international research project, not a Manhattan Project. — tap to centre the map on it The last steps to AGI should be taken by a CERN-style international research project, not a Manhattan Project. Last stated a year ago
23 Jul 2025
DH
Demis Hassabis — holds since 2025-07-23 — tap for who they are
Same subject: A compound's AI origin story is not by itself a reason to expect it to do better in the clinic. — tap to centre the map on it A compound's AI origin story is not by itself a reason to expect it to do better in the clinic. Last stated 2 years ago
13 May 2024
DL
Derek Lowe — holds since 2024-05-13 — tap for who they are
Same subject: Token prices have stayed flat because labs deliberately kept models smaller than expected in order to get more experimental cycles. — tap to centre the map on it Token prices have stayed flat because labs deliberately kept models smaller than expected in order to get more experimental cycles. Last stated 2 months ago
11 Aug 2026
RG
Ryan Greenblatt — holds since 2026-08-11 — tap for who they are
Same subject: Nvidia's real miss was not seeing that a frontier lab could never be funded by venture capital, so its compute suppliers had to become its investors. — tap to centre the map on it Nvidia's real miss was not seeing that a frontier lab could never be funded by venture capital, so its compute suppliers had to become its investors. Last stated 6 months ago
15 Apr 2026
JH
Jensen Huang — holds since 2026-04-15 — tap for who they are
Same subject: A narrow, highly accurate model can beat a general one inside its own domain, as AlphaFold did, and materials science and chip design are next. — tap to centre the map on it A narrow, highly accurate model can beat a general one inside its own domain, as AlphaFold did, and materials science and chip design are next. Last stated 3 months ago
30 Jul 2026
JD
Jeff Dean — holds since 2026-07-30 — tap for who they are
Same subject: Contemporary physical and evolutionary structure-prediction approaches fall far short of experimental accuracy without a close experimental homologue, limiting biological utility. — tap to centre the map on it Contemporary physical and evolutionary structure-prediction approaches fall far short of experimental accuracy without a close experimental homologue, limiting biological utility. Last stated 5 years ago
15 Jul 2021
DH
Demis Hassabis — holds since 2021-07-15 — tap for who they are
Same subject: Deep learning has effectively solved the problem of predicting a protein's 3D structure from its sequence. — tap to centre the map on it Deep learning has effectively solved the problem of predicting a protein's 3D structure from its sequence. Last stated a year ago
29 Jun 2025
EH
Elliot Hershberg — holds since 2025-06-29 — tap for who they are
Same subject: A persistently rising dividend yield eventually forces capital appreciation as the market rerates the stock. — tap to centre the map on it A persistently rising dividend yield eventually forces capital appreciation as the market rerates the stock. Last stated 8 months ago
3 Mar 2026
SB
Sanjay Bakshi — holds since 2026-03-03 — tap for who they are
Same subject: A proof and an explanation are different things, and a theorem can stay an unsolved expository problem long after it is proved. — tap to centre the map on it A proof and an explanation are different things, and a theorem can stay an unsolved expository problem long after it is proved. Last stated 4 months ago
30 Jun 2026
GS
Grant Sanderson — holds since 2026-06-30 — tap for who they are
Same subject: A stream of AI-written papers with any error rate at all becomes insufferable, because finding the error costs more than the paper is worth even at ninety-nine percent. — tap to centre the map on it A stream of AI-written papers with any error rate at all becomes insufferable, because finding the error costs more than the paper is worth even at ninety-nine percent. Last stated 4 months ago
30 Jun 2026
GS
Grant Sanderson — holds since 2026-06-30 — tap for who they are
Same subject: A ban on self-recursive improvement in AI models would create a big incentive for some other parts of the world to invest a lot more in compute. — tap to centre the map on it A ban on self-recursive improvement in AI models would create a big incentive for some other parts of the world to invest a lot more in compute. Last stated 4 weeks ago
22 Sept 2026
TC
Tyler Cowen — holds since 2026-09-22 — tap for who they are
Same subject: AI is already inside the recursive self-improvement loop — what the labs have shipped in recent weeks shows the cycle has started. — tap to centre the map on it AI is already inside the recursive self-improvement loop — what the labs have shipped in recent weeks shows the cycle has started. Last stated 3 months ago
3 Aug 2026
CP
Chamath Palihapitiya — holds since 2026-08-03 — tap for who they are
Same subject: AI research will be fully automated around 2030 or 2031, and AI will beat humans at essentially any job by about 2033. — tap to centre the map on it AI research will be fully automated around 2030 or 2031, and AI will beat humans at essentially any job by about 2033. Last stated 2 months ago
11 Aug 2026
RG
Ryan Greenblatt — holds since 2026-08-11 — tap for who they are
At the centre
The Human Genome Project's results have been less transformative than initially advertised relative to its cost.
Holds Read this korrent →
This work could have been run as a business; open-sourcing it simply puts the tools in more scientists' hands faster.
Holds
Effective altruism's work on the far future is not a bait and switch hiding behind its work on global health; both halves are worth defending.
Holds
An AI as good as a top researcher will not be priced like one, because it competes against the other labs rather than against humans.
Holds
A million copies of one researcher would hit diminishing returns quickly, because what research needs is people who think differently.
Holds
The last steps to AGI should be taken by a CERN-style international research project, not a Manhattan Project.
Holds
A compound's AI origin story is not by itself a reason to expect it to do better in the clinic.
Holds
Token prices have stayed flat because labs deliberately kept models smaller than expected in order to get more experimental cycles.
Holds
Nvidia's real miss was not seeing that a frontier lab could never be funded by venture capital, so its compute suppliers had to become its investors.
Holds
A narrow, highly accurate model can beat a general one inside its own domain, as AlphaFold did, and materials science and chip design are next.
Holds
Contemporary physical and evolutionary structure-prediction approaches fall far short of experimental accuracy without a close experimental homologue, limiting biological utility.
Holds
Deep learning has effectively solved the problem of predicting a protein's 3D structure from its sequence.
Holds
A persistently rising dividend yield eventually forces capital appreciation as the market rerates the stock.
Holds
A proof and an explanation are different things, and a theorem can stay an unsolved expository problem long after it is proved.
Holds
A stream of AI-written papers with any error rate at all becomes insufferable, because finding the error costs more than the paper is worth even at ninety-nine percent.
Holds
A ban on self-recursive improvement in AI models would create a big incentive for some other parts of the world to invest a lot more in compute.
Holds
AI is already inside the recursive self-improvement loop — what the labs have shipped in recent weeks shows the cycle has started.
Holds
AI research will be fully automated around 2030 or 2031, and AI will beat humans at essentially any job by about 2033.
Holds