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← A computational discovery platform does not make a biotech fast,…
17 connected korrents · 19 moments on record from 11 Jun 2006 to 20 Aug 2026.
Everything filed under chat interfaces
chat interfaces
Everything filed under design
design
Everything filed under simplicity
simplicity
Everything filed under taste
taste Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Read this korrent: A computational discovery platform does not make a biotech fast, because the thousand other steps of drug development are still the bottleneck. A computational discovery platform does not make a biotech fast, because the thousand other steps of drug development are still the bottleneck. Last stated 2 years ago
17 Sept 2024
AT
Alex Telford — holds since 2024-09-17 — tap for who they are
Same subject: Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. — tap to centre the map on it Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. Last stated 6 months ago
28 Feb 2026
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: Putting a device into the brain works in an hour, which makes it far more amenable to biology than drug discovery. — tap to centre the map on it Putting a device into the brain works in an hour, which makes it far more amenable to biology than drug discovery. Last stated 3 weeks ago
20 Aug 2026
MH
Max Hodak — holds since 2026-08-20 — tap for who they are
Same subject: The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. — tap to centre the map on it The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. Last stated 2 months ago
21 Jul 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-07-21 — tap for who they are
Same subject: AI progress is faster than people expect, and ordinary scaling can be enough to solve problems that looked very hard. — tap to centre the map on it AI progress is faster than people expect, and ordinary scaling can be enough to solve problems that looked very hard. Last stated 2 years ago
2 Feb 2025
AC
Ajeya Cotra — holds since 2023-08-29 — tap for who they are
SA
Scott Alexander — holds since 2022-09-12 — tap for who they are
MB
Miles Brundage — holds since 2025-02-02 — tap for who they are
Same subject: There is no real impediment to models running their own research loop and improving themselves at a far more rapid rate. — tap to centre the map on it There is no real impediment to models running their own research loop and improving themselves at a far more rapid rate. Last stated a month ago
30 Jul 2026
JD
Jeff Dean — holds since 2026-07-30 — tap for who they are
Same subject: Every new drug has to beat the cheap generics that came before it, and that competition with our own back catalogue is why drug discovery gets harder over time. — tap to centre the map on it Every new drug has to beat the cheap generics that came before it, and that competition with our own back catalogue is why drug discovery gets harder over time. Last stated 14 years ago
8 Mar 2012
DL
Derek Lowe — holds since 2012-03-08 — tap for who they are
Same subject: Learned approximations of slow simulators change what science is possible, by turning a six-month screening run into something you do over lunch. — tap to centre the map on it Learned approximations of slow simulators change what science is possible, by turning a six-month screening run into something you do over lunch. Last stated a month ago
30 Jul 2026
JD
Jeff Dean — holds since 2026-07-30 — tap for who they are
Same subject: A narrow, highly accurate model can beat a general one inside its own domain, as AlphaFold did, and materials science and chip design are next. — tap to centre the map on it A narrow, highly accurate model can beat a general one inside its own domain, as AlphaFold did, and materials science and chip design are next. Last stated a month ago
30 Jul 2026
JD
Jeff Dean — holds since 2026-07-30 — tap for who they are
Same subject: AI acceleration threatens 'less software': without the constraint of scarce hours, even 37signals will likely build too much. — tap to centre the map on it AI acceleration threatens 'less software': without the constraint of scarce hours, even 37signals will likely build too much. Last stated a month ago
26 Jul 2026
DH
David Heinemeier Hansson — holds since 2026-07-26 — tap for who they are
Same subject: Convergence and simplicity make for poor goals in technology; aim for clarity instead. — tap to centre the map on it Convergence and simplicity make for poor goals in technology; aim for clarity instead. Last stated 12 years ago
18 Feb 2015
FC
Frank Chimero — holds since 2015-02-18 — tap for who they are
Same subject: Savings in time feel like simplicity: when forced to wait, life seems unnecessarily complex. — tap to centre the map on it Savings in time feel like simplicity: when forced to wait, life seems unnecessarily complex. Last stated 20 years ago
11 Jun 2006
JM
John Maeda — holds since 2006-06-11 — tap for who they are
Same subject: A first draft should not be graded good or bad; it is only the material that taste then gets to act on. — tap to centre the map on it A first draft should not be graded good or bad; it is only the material that taste then gets to act on. Last stated a month ago
6 Aug 2026
GS
George Saunders — holds since 2026-08-06 — tap for who they are
Same subject: A lot of people can match a framework for taste; almost nobody can create one, and creating one is the rare skill. — tap to centre the map on it A lot of people can match a framework for taste; almost nobody can create one, and creating one is the rare skill. Last stated 11 months ago
16 Oct 2025
DF
Dylan Field — holds since 2025-10-16 — tap for who they are
Same subject: A product needs a soul, and for that it needs one person of great taste who is its living, breathing aspect and gets furious about every small detail. — tap to centre the map on it A product needs a soul, and for that it needs one person of great taste who is its living, breathing aspect and gets furious about every small detail. Last stated 17 years ago
12 Feb 2010
KS
Karri Saarinen — holds since 2010-02-12 — tap for who they are
Same subject: Chat is not AI's final form: agent-based applications increasingly outperform chat-only ones, and many different interfaces for AI will emerge. — tap to centre the map on it Chat is not AI's final form: agent-based applications increasingly outperform chat-only ones, and many different interfaces for AI will emerge. Last stated a year ago
28 Aug 2025
LW
Luke Wroblewski — holds since 2025-08-28 — tap for who they are
Same subject: Chatbot interfaces are the wrong tool for meaningful coding work, because you are mostly hoping the model recalls the right answer and correcting it requires a human in the loop. — tap to centre the map on it Chatbot interfaces are the wrong tool for meaningful coding work, because you are mostly hoping the model recalls the right answer and correcting it requires a human in the loop. Last stated 7 months ago
5 Feb 2026
MH
Mitchell Hashimoto — holds since 2026-02-05 — tap for who they are
Same subject: ChatGPT exploded because of its obvious chat interface, not its technology, which had launched earlier in a different wrapper that few noticed. — tap to centre the map on it ChatGPT exploded because of its obvious chat interface, not its technology, which had launched earlier in a different wrapper that few noticed. Last stated a year ago
12 May 2025
JZ
Julie Zhuo — holds since 2025-05-12 — tap for who they are
At the centre
A computational discovery platform does not make a biotech fast, because the thousand other steps of drug development are still the bottleneck.
Holds AT Alex TelfordRead this korrent →
Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is.
Holds RT Ruxandra Teslo
Putting a device into the brain works in an hour, which makes it far more amenable to biology than drug discovery.
Holds MH Max Hodak
The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule.
Holds AT Alex TelfordRT Ruxandra Teslo
AI progress is faster than people expect, and ordinary scaling can be enough to solve problems that looked very hard.
Holds AC Ajeya CotraSA Scott AlexanderMB Miles Brundage
There is no real impediment to models running their own research loop and improving themselves at a far more rapid rate.
Holds JD Jeff Dean
Every new drug has to beat the cheap generics that came before it, and that competition with our own back catalogue is why drug discovery gets harder over time.
Holds DL Derek Lowe
Learned approximations of slow simulators change what science is possible, by turning a six-month screening run into something you do over lunch.
Holds JD Jeff Dean
A narrow, highly accurate model can beat a general one inside its own domain, as AlphaFold did, and materials science and chip design are next.
Holds JD Jeff Dean
AI acceleration threatens 'less software': without the constraint of scarce hours, even 37signals will likely build too much.
Holds
Convergence and simplicity make for poor goals in technology; aim for clarity instead.
Holds FC Frank Chimero
Savings in time feel like simplicity: when forced to wait, life seems unnecessarily complex.
Holds JM John Maeda
A first draft should not be graded good or bad; it is only the material that taste then gets to act on.
Holds GS George Saunders
A lot of people can match a framework for taste; almost nobody can create one, and creating one is the rare skill.
Holds DF Dylan Field
A product needs a soul, and for that it needs one person of great taste who is its living, breathing aspect and gets furious about every small detail.
Holds KS Karri Saarinen
Chat is not AI's final form: agent-based applications increasingly outperform chat-only ones, and many different interfaces for AI will emerge.
Holds LW Luke Wroblewski
Chatbot interfaces are the wrong tool for meaningful coding work, because you are mostly hoping the model recalls the right answer and correcting it requires a human in the loop.
Holds
ChatGPT exploded because of its obvious chat interface, not its technology, which had launched earlier in a different wrapper that few noticed.
Holds JZ Julie Zhuo