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Max Hodak

@max-hodak · 40 positions · 0 changes of mind

Co-founder and chief executive of Science, a neurotechnology company whose retinal implant restores sight to blind patients; before founding it he spent five years at Neuralink.

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  1. It's like, you know, when we went to the moon, we did it. And so, historically, the success rate of moonshots is higher than I think people give them credit for.
    spoken · machine transcript hear it at 6:07 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 1st of 18 in this recording

  2. People have spent huge amounts of time and money looking for drugs to restore vision or to restore hearing or to stop Parkinson's or to to help paralyzed people move again. Understanding the like the biology and the molecular detail required to make a drug has been very difficult. Humanity just isn't that good at that, to be totally honest.
    spoken · machine transcript hear it at 7:13 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 2nd of 18 in this recording

  3. It's like if I put electrodes in M1, you will probably be using a computer in an hour. Um and so it's just it's easier, it's more amenable to biology in many ways.
    spoken · machine transcript hear it at 8:16 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 3rd of 18 in this recording

  4. Like, the brain very literally, very clearly, plainly is a computer in in my understanding of the world. I also view the universe generally as a computer.
    spoken · machine transcript hear it at 10:12 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 4th of 18 in this recording

  5. Yeah, I mean I think BCI is a category kind of like how pharma is a category. I think sometimes you I I'll talk to VCs and like, "Oh, we have a BCI bet." I'm like, "Do you have a drug bet? You made one bet on a drugs? Like that's that's how you think about the category?"
    spoken · machine transcript hear it at 12:26 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 5th of 18 in this recording

    venture capital

  6. It'd be pretty annoying if they just start like spontaneously getting notifications during meetings that like, "Oh, it thought that you were thinking about an Uber, therefore it decided to summon summon two for you." And so you'll probably want these to be pretty explicit.
    spoken · machine transcript hear it at 13:32 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 6th of 18 in this recording

  7. because if you can if you get vision, hearing, balance, and a kilobit per second of motor control, you're halfway to the Matrix.
    spoken · machine transcript hear it at 14:03 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 7th of 18 in this recording

  8. so I'm in the camp that like continuity is greatly important. And so people will accept significant drift in their identity over time as long as they have continuity.
    spoken · machine transcript hear it at 18:26 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 8th of 18 in this recording

  9. And so when you look inside these big AI models, the mathematical objects that you see look a lot like the things that you see in neuroscience. So if you look at how do how do these AI models represent um just like represent concepts and you look at the parts of the brain that represent concepts, you see these you see very similar geometry.
    spoken · machine transcript hear it at 20:20 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 9th of 18 in this recording

  10. I mean it feels like a lot of physics. Like if you apply enough compute to matter, you get this thing that looks like intelligence.
    spoken · machine transcript hear it at 21:06 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 10th of 18 in this recording

    physics

  11. Well, I mean ironically it's probably working on AI.
    spoken · machine transcript hear it at 22:09 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 11th of 18 in this recording

  12. Yeah, well I mean becoming profitable or at least have like having the ability to do this forever is a super high priority. Restoring vision to the blind is pretty good business if you can actually do that.
    spoken · machine transcript hear it at 22:49 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 12th of 18 in this recording

  13. the only organ that you can't even in principle transplant is the brain. The like the heart, pancreas, the liver, the lungs, as far as I'm concerned, they're really support characters. They're there to keep the brain activity interesting and and going.
    spoken · machine transcript hear it at 25:33 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 13th of 18 in this recording

  14. That world is is generated by the brain. And so, if you can get visuals the visual signal, auditory signal, balance, motor, like somatic sensory motor in and out of the brain, that is that is an end in itself. That is the central object.
    spoken · machine transcript hear it at 26:47 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 14th of 18 in this recording

  15. And I think that if we're successful, what will happen is that sense of jeopardy will fade. Like we will be we will just become much less fragile.
    spoken · machine transcript hear it at 27:59 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 15th of 18 in this recording

  16. the other extreme is if we're serious about exploring the universe and going to the stars, we are going to have to adapt ourselves to that environment. We're not going to export Earth with us everywhere we go.
    spoken · machine transcript hear it at 28:28 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 16th of 18 in this recording

  17. Well, I mean first of all, I think that talking or writing is thinking.
    spoken · machine transcript hear it at 29:18 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 17th of 18 in this recording

  18. It might turn out to be like AR AR glasses where it's just we were our attention was already fully 100% occupied and putting it on the face didn't really change that. We were already consuming all of the available time.
    spoken · machine transcript hear it at 30:40 · all korrents from this recording

    From Restoring Sight to Reimagining the Brain, with Max Hodakyoutube.com 18th of 18 in this recording

  19. 13 days earlier
  20. then you also remember that you've hired some very highly paid and talented employees. And are you saying they can't get the tools that they need? That you're spending $100,000 a week. If you wait a week to get a power supply half off, you have certainly dwarfed any possible benefit from getting it.
    spoken · machine transcript hear it at 4:25 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 1st of 22 in this recording

  21. And so what you realize is not only is this very hard to keep burn under control, but also it's just this is the inappropriate place to exercise spending review. Spending review has to come earlier. You have to have some concept of budgeting.
    spoken · machine transcript hear it at 4:44 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 2nd of 22 in this recording

  22. And so if nobody knows how much an experiment costs, like every time you like grow up a new cell line or every time we make a new a new probe in in the fab, how much does that loop cost? Nobody knows. Therefore, experiments are free. Um, it doesn't cost dollars. It costs media. And media comes from the fridge.
    spoken · machine transcript hear it at 6:54 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 3rd of 22 in this recording

  23. I think the best companies in my experience come from what might be characterized as scenes. There's like a moment that enables a new company to be born and there's a bunch that comes together that really creates this like unique nucleation for the new company.
    spoken · machine transcript hear it at 9:11 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 4th of 22 in this recording

  24. there's no one right answer, but this is a thing where you need a really defined process. There is no right answer, but a wrong answer for sure is not having something that you do very religiously as a company.
    spoken · machine transcript hear it at 10:09 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 5th of 22 in this recording

    hiring

  25. And so we can distribute the voting across a lot of the company for this initial review, which is essential because if you're doing anything cool, by the time you get a couple years into it, that top of funnel is overwhelming. And if you place any in any small group of employees or any one person in the way as a bottle bottleneck on this, they will absolutely bottleneck the whole rest of the organization.
    spoken · machine transcript hear it at 11:47 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 6th of 22 in this recording

    hiring

  26. Um which based on my experience is like this is a a very disruptive process that doesn't tend to surface issues that you don't already know about but haven't acted on because you knew that thing was there.
    spoken · machine transcript hear it at 16:00 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 7th of 22 in this recording

  27. This is a little bit different than actually literally I vector centrality but it's very similar and so we call this technique IGEN reviews and I've become convinced that this is more or less the right way to do performance reviews.
    spoken · machine transcript hear it at 17:38 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 8th of 22 in this recording

  28. But the the real theme of the talk is that rate of iteration separates success from failure. And if you can get a fast iteration loop, that really overcomes many other things you're going to run into. And this effect is so severe. I mean, if you can learn one thing every week and there's a competitor that's learning a thing every month, they will they will never matter.
    spoken · machine transcript hear it at 18:44 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 9th of 22 in this recording

  29. And so speed determines success and failure and speed is determined by infrastructure. This is driven by really boring sounding things like how well do your purchasing and recruiting and spending processes work. This is as important as how well do you understand understand the object level technical content of the thing that you're building.
    spoken · machine transcript hear it at 19:27 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 10th of 22 in this recording

    startupsinfrastructure

  30. It's like it's it's uncommon that these deep tech companies that fail because the technology doesn't work. They fail because once you end up with this organization of hundreds of people and thousand hundreds of thousands of square feet of physical infrastructure, you haven't built the systems to manage that.
    spoken · machine transcript hear it at 19:53 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 11th of 22 in this recording

    infrastructure

  31. And one of the harder lessons as a startup founder, one of the harder things I think to to really deal with is the fact that you cannot delegate your judgment. As as the CEO, you must always make decisions that make sense to you, no matter how much momentum or inertia alternatives seem to have.
    spoken · machine transcript hear it at 20:30 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 12th of 22 in this recording

    startups

  32. And so um in order to succeed your judgment has to be differentiatedly good. Now the reality might be that you don't know if your judgment is good yet. And so um one way or another you will have to find out and that means making decisions that make sense to you even when you are totally alone in that realization.
    spoken · machine transcript hear it at 21:08 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 13th of 22 in this recording

  33. Now, the good news is that in my experience, it's very difficult to actually get stuck. Um, you can get yourself into trouble and the action space is always larger than it appears.
    spoken · machine transcript hear it at 22:02 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 14th of 22 in this recording

  34. So when a field really starts to work, industry can just marshall such larger levels of resources and can just move so much faster.
    spoken · machine transcript hear it at 25:43 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 15th of 22 in this recording

  35. I think you have to have that type of competitive feedback. It is tough to know if you're exceptional um without having some legible competitive game.
    spoken · machine transcript hear it at 27:22 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 16th of 22 in this recording

  36. Now, if we had a tech if we had a magical BCI that allowed me to see the instant state of every neuron in the brain and and drive them, I think we'd figure out consciousness pretty fast. I don't think I think this is a practical problem, not a philosophical problem.
    spoken · machine transcript hear it at 31:54 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 17th of 22 in this recording

  37. It gives you these effect sizes that you just don't really see in medicine. Like if you have a patient on on a dopamineergic drug for Parkinson's that works for some period of time, but it's a it's a relatively small effect after a little while. You turn on a deep brain stimulator and a patient goes from not being able to hold a cup of water to being able to write cursive in like 10 seconds.
    spoken · machine transcript hear it at 41:08 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 18th of 22 in this recording

  38. there are definitely some ideas that are worth funding with $50 million or zero dollars, but not $5 million. Um you won't run the experiment. It'll be really frustrating experience. You'll get an ambiguous outcome.
    spoken · machine transcript hear it at 43:53 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 19th of 22 in this recording

  39. you do need to think about how do you get to revenue so that not just you can do it forever, but then you'll be valued on your long-term road map, not not valued on your probability of dying.
    spoken · machine transcript hear it at 45:34 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 20th of 22 in this recording

  40. I think one of the things that makes science the company very special is that it has both of those cultures and is able to integrate them and we're able to simultaneously do some really cool research that I think is really at the edge of the Overton window while simultaneously running clinical trials in six countries now with an approved medical device in Europe and clinical trial results in the New England Journal of Medicine.
    spoken · machine transcript hear it at 53:17 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 21st of 22 in this recording

    Europe

  41. Well, I mean, okay, even the whole basis of building Helix is contrarian. Like, I think that if you raise a series A and then you tell your investors that you're going to vibe code a purchasing system, I think that any reasonable board is going to like ask you what you're thinking.
    spoken · machine transcript hear it at 56:25 · all korrents from this recording

    Max Hodak: Average Is Not Good Enoughyoutube.com 22nd of 22 in this recording

    vibe coding