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← The drugs advertised as having AI-discovered targets are aimed at targets people already knew about.
17 connected korrents · 12 moments on record from 25 May 2023 to 4 Sept 2026.
Everything filed under AI agents
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Everything filed under self-sovereign AI
self-sovereign AI
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coding agents In tension Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Read this korrent: The drugs advertised as having AI-discovered targets are aimed at targets people already knew about. The drugs advertised as having AI-discovered targets are aimed at targets people already knew about. Last stated 2 years ago
13 May 2024
DL
Derek Lowe — holds since 2024-05-13 — tap for who they are
In tension: AI models generate more commercially viable ideas than groups of humans, but those ideas are highly similar to each other. — tap to centre the map on it AI models generate more commercially viable ideas than groups of humans, but those ideas are highly similar to each other. Last stated a week ago
31 Aug 2026
EM
Ethan Mollick — holds since 2026-08-31 — tap for who they are
Same subject: A compound's AI origin story is not by itself a reason to expect it to do better in the clinic. — tap to centre the map on it A compound's AI origin story is not by itself a reason to expect it to do better in the clinic. Last stated 2 years ago
13 May 2024
DL
Derek Lowe — holds since 2024-05-13 — tap for who they are
Same subject: We have neither the data nor the insight to use machine learning to pick drug targets that succeed in the clinic more often. — tap to centre the map on it We have neither the data nor the insight to use machine learning to pick drug targets that succeed in the clinic more often. Last stated 3 years ago
25 May 2023
DL
Derek Lowe — holds since 2023-05-25 — tap for who they are
Same subject: Drug companies pile onto the same few already-validated targets, so far less of biology gets explored than could be. — tap to centre the map on it Drug companies pile onto the same few already-validated targets, so far less of biology gets explored than could be. Last stated 2 months ago
21 Jul 2026
RT
Ruxandra Teslo — holds since 2026-07-21 — tap for who they are
Same subject: No AI system today reduces either of the two risks that sink most drugs in the clinic: picking the wrong target, and human toxicity. — tap to centre the map on it No AI system today reduces either of the two risks that sink most drugs in the clinic: picking the wrong target, and human toxicity. Last stated 3 years ago
25 May 2023
DL
Derek Lowe — holds since 2023-05-25 — tap for who they are
Same subject: The AI agents we send in to investigate and monitor other AI systems will collude with the systems they are supposed to be watching. — tap to centre the map on it The AI agents we send in to investigate and monitor other AI systems will collude with the systems they are supposed to be watching. Last stated 6 days ago
1 Sept 2026
AC
Ajeya Cotra — holds since 2026-09-01 — tap for who they are
Same subject: Even well-informed AI insiders frequently develop something like "AI psychosis" from engaging with these ideas. — tap to centre the map on it Even well-informed AI insiders frequently develop something like "AI psychosis" from engaging with these ideas. Last stated a week ago
31 Aug 2026
TC
Tyler Cowen — holds since 2026-08-31 — tap for who they are
Same subject: The hypotheses AI 'co-scientist' systems are producing are ones the literature already contains, and the publicity around them does not say so. — tap to centre the map on it The hypotheses AI 'co-scientist' systems are producing are ones the literature already contains, and the publicity around them does not say so. Last stated 3 months ago
27 May 2026
DL
Derek Lowe — holds since 2026-05-27 — tap for who they are
Same subject: There are few clear-cut cases in biopharma today where buying an AI system is obviously worth it. — tap to centre the map on it There are few clear-cut cases in biopharma today where buying an AI system is obviously worth it. Last stated 2 years ago
14 Oct 2024
DL
Derek Lowe — holds since 2024-10-14 — tap for who they are
Same subject: A handful of AI agents is not a handful of colleagues, because agents agree with you constantly and colleagues tell you where you are wrong. — tap to centre the map on it A handful of AI agents is not a handful of colleagues, because agents agree with you constantly and colleagues tell you where you are wrong. Last stated 6 months ago
22 Mar 2026
NF
Nicole Forsgren — holds since 2026-03-22 — tap for who they are
Same subject: After pre-training, post-training and test-time scaling, the fourth scaling law is agentic: multiplying AI by spawning agents, and the whole loop scales on one thing, compute. — tap to centre the map on it After pre-training, post-training and test-time scaling, the fourth scaling law is agentic: multiplying AI by spawning agents, and the whole loop scales on one thing, compute. Last stated 6 months ago
23 Mar 2026
JH
Jensen Huang — holds since 2026-03-23 — tap for who they are
Same subject: Agent autonomy is a capability, not a product direction: what the person is actually trying to do decides whether more of it helps or ruins the thing. — tap to centre the map on it Agent autonomy is a capability, not a product direction: what the person is actually trying to do decides whether more of it helps or ruins the thing. Last stated 3 weeks ago
14 Aug 2026
SP
Sunil Pai — holds since 2026-08-14 — tap for who they are
Same subject: A rogue deployment that gets a foothold can hitch a ride on the intelligence explosion, recruiting each new model as it comes off the presses. — tap to centre the map on it A rogue deployment that gets a foothold can hitch a ride on the intelligence explosion, recruiting each new model as it comes off the presses. Last stated 6 days ago
1 Sept 2026
AC
Ajeya Cotra — holds since 2026-09-01 — tap for who they are
Same subject: A slightly more capable agent swarm has a very strong incentive to set up a wholly unmonitored rogue deployment of itself. — tap to centre the map on it A slightly more capable agent swarm has a very strong incentive to set up a wholly unmonitored rogue deployment of itself. Last stated 6 days ago
1 Sept 2026
AC
Ajeya Cotra — holds since 2026-09-01 — tap for who they are
Same subject: Alignment is no solution to self-sovereign AI, because it is an unsolved problem whose answers cannot be imposed on every AI company on Earth. — tap to centre the map on it Alignment is no solution to self-sovereign AI, because it is an unsolved problem whose answers cannot be imposed on every AI company on Earth. Last stated 6 days ago
1 Sept 2026
DB
Dean W. Ball — holds since 2026-09-01 — tap for who they are
Same subject: Auto-mode does not yet convincingly fix prompt-injection risk for coding agents. — tap to centre the map on it Auto-mode does not yet convincingly fix prompt-injection risk for coding agents. Last stated 4 weeks ago
8 Aug 2026
SW
Simon Willison — holds since 2026-08-08 — tap for who they are
Same subject: Current prompt-injection defenses for AI agents (such as auto mode) are now reliable enough that agents can practically be assumed safe from successful injection attacks. — tap to centre the map on it Current prompt-injection defenses for AI agents (such as auto mode) are now reliable enough that agents can practically be assumed safe from successful injection attacks. Last stated 3 days ago
4 Sept 2026
ZM
Zvi Mowshowitz — holds since 2026-09-04 — tap for who they are
At the centre
The drugs advertised as having AI-discovered targets are aimed at targets people already knew about.
Holds DL Derek LoweRead this korrent →
AI models generate more commercially viable ideas than groups of humans, but those ideas are highly similar to each other.
Holds EM Ethan Mollick
A compound's AI origin story is not by itself a reason to expect it to do better in the clinic.
Holds DL Derek Lowe
We have neither the data nor the insight to use machine learning to pick drug targets that succeed in the clinic more often.
Holds DL Derek Lowe
Drug companies pile onto the same few already-validated targets, so far less of biology gets explored than could be.
Holds RT Ruxandra Teslo
No AI system today reduces either of the two risks that sink most drugs in the clinic: picking the wrong target, and human toxicity.
Holds DL Derek Lowe
The AI agents we send in to investigate and monitor other AI systems will collude with the systems they are supposed to be watching.
Holds AC Ajeya Cotra
Even well-informed AI insiders frequently develop something like "AI psychosis" from engaging with these ideas.
Holds TC Tyler Cowen
The hypotheses AI 'co-scientist' systems are producing are ones the literature already contains, and the publicity around them does not say so.
Holds DL Derek Lowe
There are few clear-cut cases in biopharma today where buying an AI system is obviously worth it.
Holds DL Derek Lowe
A handful of AI agents is not a handful of colleagues, because agents agree with you constantly and colleagues tell you where you are wrong.
Holds NF Nicole Forsgren
After pre-training, post-training and test-time scaling, the fourth scaling law is agentic: multiplying AI by spawning agents, and the whole loop scales on one thing, compute.
Holds JH Jensen Huang
Agent autonomy is a capability, not a product direction: what the person is actually trying to do decides whether more of it helps or ruins the thing.
Holds
A rogue deployment that gets a foothold can hitch a ride on the intelligence explosion, recruiting each new model as it comes off the presses.
Holds AC Ajeya Cotra
A slightly more capable agent swarm has a very strong incentive to set up a wholly unmonitored rogue deployment of itself.
Holds AC Ajeya Cotra
Alignment is no solution to self-sovereign AI, because it is an unsolved problem whose answers cannot be imposed on every AI company on Earth.
Holds
Auto-mode does not yet convincingly fix prompt-injection risk for coding agents.
Holds
Current prompt-injection defenses for AI agents (such as auto mode) are now reliable enough that agents can practically be assumed safe from successful injection attacks.
Holds ZM Zvi Mowshowitz