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← R&D spending varies more than tenfold across diseases for no good…
17 connected korrents · 15 moments from 8 Jan 2013 to 14 Aug 2026.
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Psychotherapy Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Read this korrent: R&D spending varies more than tenfold across diseases for no good reason, which is where the best opportunities in science funding are. R&D spending varies more than tenfold across diseases for no good reason, which is where the best opportunities in science funding are. Last stated a year ago
29 May 2025
JT
Jacob Trefethen — holds since 2025-05-29 — tap for who they are
Same subject: Some ideas are worth funding with fifty million dollars or with nothing, and never with five million, because underfunding buys you an ambiguous outcome instead of an answer. — tap to centre the map on it Some ideas are worth funding with fifty million dollars or with nothing, and never with five million, because underfunding buys you an ambiguous outcome instead of an answer. Last stated 2 months ago
7 Aug 2026
MH
Max Hodak — holds since 2026-08-07 — tap for who they are
Same subject: Rich governments need to spend more on research and development, and health and education need better measurement — tap to centre the map on it Rich governments need to spend more on research and development, and health and education need better measurement
BG
Bill Gates — holds since c. 2010 — tap for who they are
Same subject: What limits science is how it is funded and organised, not how much money it gets. — tap to centre the map on it What limits science is how it is funded and organised, not how much money it gets. Last stated 7 years ago
23 Jun 2019
JR
José Luis Ricón — holds since 2019-06-23 — tap for who they are
Same subject: The pace of medical innovation can be sped up or slowed down by policy, funding and institutional choices. — tap to centre the map on it The pace of medical innovation can be sped up or slowed down by policy, funding and institutional choices. Last stated 10 months ago
28 Dec 2025
SD
Saloni Dattani — holds since 2025-12-28 — tap for who they are
Same subject: Ten billion dollars over ten years would deliver most of a list of missing life-saving health technologies, so their absence is a funding choice rather than a scientific limit. — tap to centre the map on it Ten billion dollars over ten years would deliver most of a list of missing life-saving health technologies, so their absence is a funding choice rather than a scientific limit. Last stated 3 years ago
2 Feb 2024
JT
Jacob Trefethen — holds since 2024-02-02 — tap for who they are
Same subject: Pharmaceutical R&D productivity has fallen for decades: far more money spent per drug, with no matching improvement in the odds a candidate reaches the market. — tap to centre the map on it Pharmaceutical R&D productivity has fallen for decades: far more money spent per drug, with no matching improvement in the odds a candidate reaches the market. Last stated 3 months ago
21 Jul 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-07-21 — tap for who they are
Same subject: Infectious diseases get far less industry R&D per death than non-communicable ones, because they mostly kill people in countries where a cure pays less. — tap to centre the map on it Infectious diseases get far less industry R&D per death than non-communicable ones, because they mostly kill people in countries where a cure pays less. Last stated a year ago
29 May 2025
JT
Jacob Trefethen — holds since 2025-05-29 — tap for who they are
Same subject: How long a trial takes decides which diseases get drugs at all, because capital flows to the indications whose endpoints can be measured quickly. — tap to centre the map on it How long a trial takes decides which diseases get drugs at all, because capital flows to the indications whose endpoints can be measured quickly. Last stated 8 months ago
28 Feb 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: A first-time founder has an advantage over a repeat winner, because past success makes it too easy to raise money and hire against a big vision before there is product-market fit. — tap to centre the map on it A first-time founder has an advantage over a repeat winner, because past success makes it too easy to raise money and hire against a big vision before there is product-market fit. Last stated 4 months ago
14 Jun 2026
MP
Mark Pincus — holds since 2026-06-14 — tap for who they are
Same subject: A founder should take half the valuation if it buys all of the control, because the right to be wrong in your own way is what founding was for. — tap to centre the map on it A founder should take half the valuation if it buys all of the control, because the right to be wrong in your own way is what founding was for. Last stated 5 months ago
2 Jun 2026
MP
Mark Pincus — holds since 2026-06-02 — tap for who they are
Same subject: About 5% is the most common final ownership stake for the founder of a VC-funded startup that works out. — tap to centre the map on it About 5% is the most common final ownership stake for the founder of a VC-funded startup that works out. Last stated 3 months ago
18 Jul 2026
PL
Pieter Levels — holds since 2026-07-18 — tap for who they are
Same subject: “Why now?” is the wrong question to make a founder answer — the honest answer can simply be that you started now. — tap to centre the map on it “Why now?” is the wrong question to make a founder answer — the honest answer can simply be that you started now. Last stated 3 months ago
28 Jul 2026
BS
Blake Scholl — holds since 2026-07-28 — tap for who they are
Same subject: A belief nobody else shares is a warning, and a belief everybody shares is also a warning; the right number of people who agree with you is small but not zero. — tap to centre the map on it A belief nobody else shares is a warning, and a belief everybody shares is also a warning; the right number of people who agree with you is small but not zero. Last stated 3 months ago
28 Jul 2026
SA
Sam Altman — holds since 2026-07-28 — tap for who they are
Same subject: A business succeeds through a small number of highly effective distribution channels, not many mediocre ones. — tap to centre the map on it A business succeeds through a small number of highly effective distribution channels, not many mediocre ones. Last stated 3 years ago
17 Feb 2024
AW
Adam Wiggins — holds since 2024-02-17 — tap for who they are
Same subject: A contest between five paid firms is not the way to get good creative work. — tap to centre the map on it A contest between five paid firms is not the way to get good creative work. Last stated 2 months ago
14 Aug 2026
SK
Susan Kare — holds since 2026-08-14 — tap for who they are
Same subject: A feeling of responsibility is probably the greatest inhibitor of creativity; great ideas came from people not paid to have them — tap to centre the map on it A feeling of responsibility is probably the greatest inhibitor of creativity; great ideas came from people not paid to have them
IA
Isaac Asimov — holds since c. 1959 — tap for who they are
Same subject: A free-wheeling, anarchic neural organization may be the secret of human creativity, at the price of susceptibility to mental illness — tap to centre the map on it A free-wheeling, anarchic neural organization may be the secret of human creativity, at the price of susceptibility to mental illness Last stated 14 years ago
8 Jan 2013
DD
Daniel Dennett — holds since 2013-01-08 — tap for who they are
At the centre
R&D spending varies more than tenfold across diseases for no good reason, which is where the best opportunities in science funding are.
Holds Read this korrent →
Some ideas are worth funding with fifty million dollars or with nothing, and never with five million, because underfunding buys you an ambiguous outcome instead of an answer.
Holds
Rich governments need to spend more on research and development, and health and education need better measurement
Last stated c. 2010
Holds
What limits science is how it is funded and organised, not how much money it gets.
Holds
The pace of medical innovation can be sped up or slowed down by policy, funding and institutional choices.
Holds
Ten billion dollars over ten years would deliver most of a list of missing life-saving health technologies, so their absence is a funding choice rather than a scientific limit.
Holds
Pharmaceutical R&D productivity has fallen for decades: far more money spent per drug, with no matching improvement in the odds a candidate reaches the market.
Holds
Infectious diseases get far less industry R&D per death than non-communicable ones, because they mostly kill people in countries where a cure pays less.
Holds
How long a trial takes decides which diseases get drugs at all, because capital flows to the indications whose endpoints can be measured quickly.
Holds
A first-time founder has an advantage over a repeat winner, because past success makes it too easy to raise money and hire against a big vision before there is product-market fit.
Holds
A founder should take half the valuation if it buys all of the control, because the right to be wrong in your own way is what founding was for.
Holds
About 5% is the most common final ownership stake for the founder of a VC-funded startup that works out.
Holds
“Why now?” is the wrong question to make a founder answer — the honest answer can simply be that you started now.
Holds
A belief nobody else shares is a warning, and a belief everybody shares is also a warning; the right number of people who agree with you is small but not zero.
Holds
A business succeeds through a small number of highly effective distribution channels, not many mediocre ones.
Holds
A contest between five paid firms is not the way to get good creative work.
Holds
A feeling of responsibility is probably the greatest inhibitor of creativity; great ideas came from people not paid to have them
Last stated c. 1959
Holds
A free-wheeling, anarchic neural organization may be the secret of human creativity, at the price of susceptibility to mental illness
Holds