korrents

On the map

Tap a claim on the ring to put it at the centre.

← Every new drug has to beat the cheap generics that came before it, and…

17 connected korrents · 17 moments on record from 11 Jun 2006 to 7 Sept 2026.

Everything filed under China China Everything filed under design design Everything filed under simplicity simplicity Everything filed under America America Same subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subject Read this korrent: Every new drug has to beat the cheap generics that came before it, and that competition with our own back catalogue is why drug discovery gets harder over time. Every new drug has to beat the cheapgenerics that came before it, and thatcompetition with our own back catalogue iswhy drug discovery gets harder over time. Last stated 14 years ago 8 Mar 2012 DL Derek Lowe — holds since 2012-03-08 — tap for who they are Same subject: The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. — tap to centre the map on it The hard part of drug discovery isknowing what to make - which targetis worth drugging - not designingthe molecule. Last stated 2 months ago 21 Jul 2026 AT Alex Telford — holds since 2023-12-23 — tap for who they are RT Ruxandra Teslo — holds since 2026-07-21 — tap for who they are Same subject: Pharmaceutical R&D productivity has fallen for decades: far more money spent per drug, with no matching improvement in the odds a candidate reaches the market. — tap to centre the map on it Pharmaceutical R&D productivity hasfallen for decades: far more moneyspent per drug, with no matchingimprovement in the odds a candidatereaches the market. Last stated 2 months ago 21 Jul 2026 AT Alex Telford — holds since 2023-12-23 — tap for who they are RT Ruxandra Teslo — holds since 2026-07-21 — tap for who they are Same subject: A compound's AI origin story is not by itself a reason to expect it to do better in the clinic. — tap to centre the map on it A compound's AI origin story is notby itself a reason to expect it todo better in the clinic. Last stated 2 years ago 13 May 2024 DL Derek Lowe — holds since 2024-05-13 — tap for who they are Same subject: The West has not yet internalised that China is a source of genuinely new drugs, not just a maker of ingredients and copies. — tap to centre the map on it The West has not yet internalisedthat China is a source of genuinelynew drugs, not just a maker ofingredients and copies. Last stated 2 years ago 20 Dec 2024 AT Alex Telford — holds since 2024-12-20 — tap for who they are Same subject: Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. — tap to centre the map on it Better drug candidates do notshorten clinical trials, because atrial's duration is set byoperational and regulatory frictionrather than by how good the drug is. Last stated 6 months ago 28 Feb 2026 RT Ruxandra Teslo — holds since 2026-02-28 — tap for who they are Same subject: Drug research is heading, at speed, for a world in which fewer and fewer useful medicines are discovered while more and more people want them. — tap to centre the map on it Drug research is heading, at speed,for a world in which fewer and feweruseful medicines are discoveredwhile more and more people wantthem. Last stated 14 years ago 8 Mar 2012 DL Derek Lowe — holds since 2012-03-08 — tap for who they are Same subject: This work could have been run as a business; open-sourcing it simply puts the tools in more scientists' hands faster. — tap to centre the map on it This work could have been run as abusiness; open-sourcing it simplyputs the tools in more scientists'hands faster. Last stated 3 months ago 10 Jun 2026 MZ Mark Zuckerberg — holds since 2026-06-10 — tap for who they are Same subject: A narrow, highly accurate model can beat a general one inside its own domain, as AlphaFold did, and materials science and chip design are next. — tap to centre the map on it A narrow, highly accurate model canbeat a general one inside its owndomain, as AlphaFold did, andmaterials science and chip designare next. Last stated a month ago 30 Jul 2026 JD Jeff Dean — holds since 2026-07-30 — tap for who they are Same subject: A Chinese crewed landing on the Moon before America returns would be a defeat for the free world. — tap to centre the map on it A Chinese crewed landing on the Moonbefore America returns would be adefeat for the free world. Last stated 3 weeks ago 18 Aug 2026 CH Casey Handmer — holds since 2025-10-31 — tap for who they are EB Eric Berger — holds since 2026-08-18 — tap for who they are Same subject: A country cannot fund its own industrial strategy and call the same policy cheating when China does it. — tap to centre the map on it A country cannot fund its ownindustrial strategy and call thesame policy cheating when China doesit. Last stated a year ago 15 May 2025 HR Hannah Ritchie — holds since 2025-05-15 — tap for who they are Same subject: A few square miles at the Moon's south pole are the only lunar real estate that matters, and whoever gets there first sets the terms. — tap to centre the map on it A few square miles at the Moon'ssouth pole are the only lunar realestate that matters, and whoevergets there first sets the terms. Last stated 3 weeks ago 18 Aug 2026 EB Eric Berger — holds since 2026-08-18 — tap for who they are Same subject: A country cannot have radical technological breakthroughs and also refuse to tolerate uncomfortably rich people, because the financial system it resents is what funds the innovation. — tap to centre the map on it A country cannot have radicaltechnological breakthroughs and alsorefuse to tolerate uncomfortablyrich people, because the financialsystem it resents is what funds theinnovation. Last stated a year ago 13 Aug 2025 KJ Keyu Jin — holds since 2025-08-13 — tap for who they are Same subject: A country's large trade deficit in manufactured goods reduces its manufacturing employment below what it would be with balanced trade. — tap to centre the map on it A country's large trade deficit inmanufactured goods reduces itsmanufacturing employment below whatit would be with balanced trade. Last stated today 7 Sept 2026 PK Paul Krugman — holds since 2026-09-07 — tap for who they are Same subject: A large, sustained AI capability lead by either the US or China could shift the global balance of power between them. — tap to centre the map on it A large, sustained AI capabilitylead by either the US or China couldshift the global balance of powerbetween them. Last stated 2 days ago 5 Sept 2026 NS Noah Smith — holds since 2026-09-05 — tap for who they are Same subject: AI acceleration threatens 'less software': without the constraint of scarce hours, even 37signals will likely build too much. — tap to centre the map on it AI acceleration threatens 'lesssoftware': without the constraint ofscarce hours, even 37signals willlikely build too much. Last stated a month ago 26 Jul 2026 DH David Heinemeier Hansson — holds since 2026-07-26 — tap for who they are Same subject: Convergence and simplicity make for poor goals in technology; aim for clarity instead. — tap to centre the map on it Convergence and simplicity make forpoor goals in technology; aim forclarity instead. Last stated 12 years ago 18 Feb 2015 FC Frank Chimero — holds since 2015-02-18 — tap for who they are Same subject: Savings in time feel like simplicity: when forced to wait, life seems unnecessarily complex. — tap to centre the map on it Savings in time feel likesimplicity: when forced to wait,life seems unnecessarily complex. Last stated 20 years ago 11 Jun 2006 JM John Maeda — holds since 2006-06-11 — tap for who they are
same subject or similar wordinga cloud: claims about one subject, named for itbar: when it was last stated, on a scale from 2006 to today (stretched back to the oldest claim here) — full is todaya face: someone on record holding the claim — tap it for who they are

At the centre Every new drug has to beat the cheap generics that came before it, and that competition with our own back catalogue is why drug discovery gets harder over time. Last stated 8 Mar 2012 · 14 years ago Holds Derek Lowe Read this korrent →