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← New technologies can meaningfully improve R&D productivity in drug development.
17 connected korrents · 13 moments from 15 Jul 2021 to 27 Sept 2026.
Everything filed under AI and science
AI and science
Everything filed under mathematics
mathematics
Everything filed under protein structure prediction
protein structure prediction
Everything filed under recursive self-improvement
recursive self-improvement
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innovation
Everything filed under design
design Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Read this korrent: New technologies can meaningfully improve R&D productivity in drug development. New technologies can meaningfully improve R&D productivity in drug development. Last stated 6 months ago
12 Apr 2026
EH
Elliot Hershberg — holds since 2026-04-12 — tap for who they are
Same subject: Pharmaceutical R&D productivity has fallen for decades: far more money spent per drug, with no matching improvement in the odds a candidate reaches the market. — tap to centre the map on it Pharmaceutical R&D productivity has fallen for decades: far more money spent per drug, with no matching improvement in the odds a candidate reaches the market. Last stated 2 months ago
21 Jul 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-07-21 — tap for who they are
Same subject: Drug discovery has become less efficient over time despite continued technological progress. — tap to centre the map on it Drug discovery has become less efficient over time despite continued technological progress. Last stated 8 months ago
18 Jan 2026
EH
Elliot Hershberg — holds since 2026-01-18 — tap for who they are
Same subject: Biotech R&D efficiency and pharma R&D efficiency are not the same thing and should not be conflated. — tap to centre the map on it Biotech R&D efficiency and pharma R&D efficiency are not the same thing and should not be conflated. Last stated 6 months ago
12 Apr 2026
EH
Elliot Hershberg — holds since 2026-04-12 — tap for who they are
Same subject: The pharmaceutical productivity crisis has no single villain: nearly every part of discovery and development got gradually harder and more expensive at once. — tap to centre the map on it The pharmaceutical productivity crisis has no single villain: nearly every part of discovery and development got gradually harder and more expensive at once. Last stated 3 years ago
23 Dec 2023
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
Same subject: The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. — tap to centre the map on it The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. Last stated 2 months ago
21 Jul 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-07-21 — tap for who they are
Same subject: No technology, including drug discovery technologies, is immune to the eventual pull toward commoditization. — tap to centre the map on it No technology, including drug discovery technologies, is immune to the eventual pull toward commoditization. Last stated 2 years ago
16 Mar 2025
EH
Elliot Hershberg — holds since 2025-03-16 — tap for who they are
Same subject: Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. — tap to centre the map on it Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. Last stated 7 months ago
28 Feb 2026
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: Deep learning is not yet ready for the task that would actually add value in drug development: predicting safety and efficacy in humans. — tap to centre the map on it Deep learning is not yet ready for the task that would actually add value in drug development: predicting safety and efficacy in humans. Last stated 3 years ago
23 Dec 2023
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
Same subject: Contemporary physical and evolutionary structure-prediction approaches fall far short of experimental accuracy without a close experimental homologue, limiting biological utility. — tap to centre the map on it Contemporary physical and evolutionary structure-prediction approaches fall far short of experimental accuracy without a close experimental homologue, limiting biological utility. Last stated 5 years ago
15 Jul 2021
DH
Demis Hassabis — holds since 2021-07-15 — tap for who they are
Same subject: Deep learning has effectively solved the problem of predicting a protein's 3D structure from its sequence. — tap to centre the map on it Deep learning has effectively solved the problem of predicting a protein's 3D structure from its sequence. Last stated a year ago
29 Jun 2025
EH
Elliot Hershberg — holds since 2025-06-29 — tap for who they are
Same subject: Existing protein structure prediction methods fall far short of atomic accuracy when no homologous structure is available. — tap to centre the map on it Existing protein structure prediction methods fall far short of atomic accuracy when no homologous structure is available. Last stated 5 years ago
15 Jul 2021
DH
Demis Hassabis — holds since 2021-07-15 — tap for who they are
Same subject: A persistently rising dividend yield eventually forces capital appreciation as the market rerates the stock. — tap to centre the map on it A persistently rising dividend yield eventually forces capital appreciation as the market rerates the stock. Last stated 7 months ago
3 Mar 2026
SB
Sanjay Bakshi — holds since 2026-03-03 — tap for who they are
Same subject: A proof and an explanation are different things, and a theorem can stay an unsolved expository problem long after it is proved. — tap to centre the map on it A proof and an explanation are different things, and a theorem can stay an unsolved expository problem long after it is proved. Last stated 3 months ago
30 Jun 2026
GS
Grant Sanderson — holds since 2026-06-30 — tap for who they are
Same subject: A stream of AI-written papers with any error rate at all becomes insufferable, because finding the error costs more than the paper is worth even at ninety-nine percent. — tap to centre the map on it A stream of AI-written papers with any error rate at all becomes insufferable, because finding the error costs more than the paper is worth even at ninety-nine percent. Last stated 3 months ago
30 Jun 2026
GS
Grant Sanderson — holds since 2026-06-30 — tap for who they are
Same subject: AI is already inside the recursive self-improvement loop — what the labs have shipped in recent weeks shows the cycle has started. — tap to centre the map on it AI is already inside the recursive self-improvement loop — what the labs have shipped in recent weeks shows the cycle has started. Last stated 2 months ago
3 Aug 2026
CP
Chamath Palihapitiya — holds since 2026-08-03 — tap for who they are
Same subject: AI research will be fully automated around 2030 or 2031, and AI will beat humans at essentially any job by about 2033. — tap to centre the map on it AI research will be fully automated around 2030 or 2031, and AI will beat humans at essentially any job by about 2033. Last stated 2 months ago
11 Aug 2026
RG
Ryan Greenblatt — holds since 2026-08-11 — tap for who they are
Same subject: AI self-improvement may not be powerful enough to overcome diminishing returns. — tap to centre the map on it AI self-improvement may not be powerful enough to overcome diminishing returns. Last stated 5 days ago
27 Sept 2026
RN
Ramez Naam — holds since 2026-09-27 — tap for who they are