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← Manufacturing and batch-release requirements, not biology, are what kill most promising cell and gene therapies.
10 connected korrents · 11 moments on record from 8 May 2024 to 1 Sept 2026.
Everything filed under dementia
dementia
Everything filed under motivation
motivation
Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject
Read this korrent: Manufacturing and batch-release requirements, not biology, are what kill most promising cell and gene therapies.
Manufacturing and batch-release requirements, not biology, are what kill most promising cell and gene therapies.
Last stated 3 months ago
10 Jun 2026
RT
Ruxandra Teslo — holds since 2026-06-10 — tap for who they are
Same subject: Investment will keep draining out of cell and gene therapy until manufacturing and regulatory risk become possible to underwrite. — tap to centre the map on it
Investment will keep draining out of cell and gene therapy until manufacturing and regulatory risk become possible to underwrite.
Last stated 3 months ago
10 Jun 2026
RT
Ruxandra Teslo — holds since 2026-06-10 — tap for who they are
Same subject: Drug companies pile onto the same few already-validated targets, so far less of biology gets explored than could be. — tap to centre the map on it
Drug companies pile onto the same few already-validated targets, so far less of biology gets explored than could be.
Last stated 2 months ago
21 Jul 2026
RT
Ruxandra Teslo — holds since 2026-07-21 — tap for who they are
Same subject: Humanity is not good enough at molecular biology to make drugs that restore vision or hearing or stop Parkinson's. — tap to centre the map on it
Humanity is not good enough at molecular biology to make drugs that restore vision or hearing or stop Parkinson's.
Last stated 3 weeks ago
20 Aug 2026
MH
Max Hodak — holds since 2026-08-20 — tap for who they are
Same subject: The tools that make biology powerful for medicine are the same tools that make it dangerous, so the benefits and the misuse risk cannot be separated. — tap to centre the map on it
The tools that make biology powerful for medicine are the same tools that make it dangerous, so the benefits and the misuse risk cannot be separated.
Last stated a year ago
2 Aug 2025
KE
Kevin Esvelt — holds since 2024-05-08 — tap for who they are
JT
Jacob Trefethen — holds since 2025-08-02 — tap for who they are
Same subject: About half of all dementia is preventable, and most of that preventable half is Alzheimer's disease and vascular dementia. — tap to centre the map on it
About half of all dementia is preventable, and most of that preventable half is Alzheimer's disease and vascular dementia.
Last stated 2 months ago
20 Jul 2026
TW
Tommy Wood — holds since 2026-07-20 — tap for who they are
Same subject: Alzheimer's disease and dementia are not the same thing: a fifth to a third of people whose brains carry the pathology never became demented. — tap to centre the map on it
Alzheimer's disease and dementia are not the same thing: a fifth to a third of people whose brains carry the pathology never became demented.
Last stated 2 weeks ago
24 Aug 2026
MH
Masud Husain — holds since 2026-08-24 — tap for who they are
Same subject: Alzheimer's pathology in the brain does not settle whether a person has dementia: the nuns' brains were full of plaques and tangles while they went on functioning normally. — tap to centre the map on it
Alzheimer's pathology in the brain does not settle whether a person has dementia: the nuns' brains were full of plaques and tangles while they went on functioning normally.
Last stated 2 months ago
13 Jul 2026
AC
Alan Castel — holds since 2026-07-13 — tap for who they are
Same subject: Action comes before motivation: you do first and feel afterwards, not the other way round. — tap to centre the map on it
Action comes before motivation: you do first and feel afterwards, not the other way round.
Last stated 11 months ago
30 Sept 2025
LF
Lex Fridman — holds since 2025-09-30 — tap for who they are
Same subject: AI is not a limited-time sale: the people furthest along are working harder than ever, and they need to stop harvesting dopamine as if it ends in two weeks. — tap to centre the map on it
AI is not a limited-time sale: the people furthest along are working harder than ever, and they need to stop harvesting dopamine as if it ends in two weeks.
Last stated 5 months ago
8 Apr 2026
DH
David Heinemeier Hansson — holds since 2026-04-08 — tap for who they are
Same subject: AI systems should be understood as something between airplanes and humans, since it can no longer be assumed they lack humanlike motivations. — tap to centre the map on it
AI systems should be understood as something between airplanes and humans, since it can no longer be assumed they lack humanlike motivations.
Last stated 6 days ago
1 Sept 2026
SA
Scott Alexander — holds since 2026-09-01 — tap for who they are
same subject or similar wording a cloud: claims about one subject, named for it bar: when it was last stated, on a scale from 2015 to today — full is today a face: someone on record holding the claim — tap it for who they are