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← A large national research cohort must transition from a pull model to…

14 connected korrents · 11 moments from 14 Feb 2015 to 30 Jul 2026.

Everything filed under AI and science AI and science Everything filed under innovation innovation Everything filed under LLMs LLMs Everything filed under recursive self-improvement recursive self-improvement Everything filed under design design Same subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subjectSame subject Read this korrent: A large national research cohort must transition from a pull model to a push model of medical research to achieve desired scale and cost. A large national research cohort musttransition from a pull model to a pushmodel of medical research to achievedesired scale and cost. Last stated 12 years ago by 14 Feb 2015 MM Matt Might — holds since 2015-02-14 — tap for who they are Same subject: A million copies of one researcher would hit diminishing returns quickly, because what research needs is people who think differently. — tap to centre the map on it A million copies of one researcherwould hit diminishing returnsquickly, because what research needsis people who think differently. Last stated 11 months ago 25 Nov 2025 IS Ilya Sutskever — holds since 2025-11-25 — tap for who they are Same subject: The inclusion of children in a national research cohort is necessary to capture the most valuable genotype-phenotype pairings. — tap to centre the map on it The inclusion of children in anational research cohort isnecessary to capture the mostvaluable genotype-phenotypepairings. Last stated 12 years ago by 14 Feb 2015 MM Matt Might — holds since 2015-02-14 — tap for who they are Same subject: A federated model of distributed, heterogeneous electronic health records is the only feasible model for a large research cohort in the near term. — tap to centre the map on it A federated model of distributed,heterogeneous electronic healthrecords is the only feasible modelfor a large research cohort in thenear term. Last stated 12 years ago by 14 Feb 2015 MM Matt Might — holds since 2015-02-14 — tap for who they are Same subject: Changing societal outcomes requires changing minds, and the credibility many diverse co-authors lend to a conclusion is hard to replicate with AI. — tap to centre the map on it Changing societal outcomes requireschanging minds, and the credibilitymany diverse co-authors lend to aconclusion is hard to replicate withAI. Last stated a year ago 27 Aug 2025 MB Miles Brundage — holds since 2025-08-27 — tap for who they are Same subject: There is no real impediment to models running their own research loop and improving themselves at a far more rapid rate. — tap to centre the map on it There is no real impediment tomodels running their own researchloop and improving themselves at afar more rapid rate. Last stated 3 months ago 30 Jul 2026 JD Jeff Dean — holds since 2026-07-30 — tap for who they are Same subject: A compound's AI origin story is not by itself a reason to expect it to do better in the clinic. — tap to centre the map on it A compound's AI origin story is notby itself a reason to expect it todo better in the clinic. Last stated 2 years ago 13 May 2024 DL Derek Lowe — holds since 2024-05-13 — tap for who they are Same subject: A computational discovery platform does not make a biotech fast, because the thousand other steps of drug development are still the bottleneck. — tap to centre the map on it A computational discovery platformdoes not make a biotech fast,because the thousand other steps ofdrug development are still thebottleneck. Last stated 2 years ago 17 Sept 2024 AT Alex Telford — holds since 2024-09-17 — tap for who they are Same subject: A computational method can regularly predict protein structures with atomic accuracy even when no similar structure is known. — tap to centre the map on it A computational method can regularlypredict protein structures withatomic accuracy even when no similarstructure is known. Last stated 5 years ago 15 Jul 2021 DH Demis Hassabis — holds since 2021-07-15 — tap for who they are Same subject: "Lots of anonymous people worked it out by trial and error" is never the real story of an invention: on closer investigation, identifiable people always turn out to be responsible. — tap to centre the map on it "Lots of anonymous people worked itout by trial and error" is never thereal story of an invention: oncloser investigation, identifiablepeople always turn out to beresponsible. Last stated 3 years ago 25 Oct 2023 AH Anton Howes — holds since 2023-10-25 — tap for who they are Same subject: A business can have market fit, real advantages, and sustained effort behind a hard product and still fail if it doesn't give customers a strong enough reason to switch from what they already use. — tap to centre the map on it A business can have market fit, realadvantages, and sustained effortbehind a hard product and still failif it doesn't give customers astrong enough reason to switch fromwhat they already use. Last stated 5 months ago 2 Jun 2026 JJ Justin Jackson — holds since 2026-06-02 — tap for who they are Same subject: A capability existing is not the same as a capability being absorbed: how fast a technology changes the world is not set by how fast the technology improves. — tap to centre the map on it A capability existing is not thesame as a capability being absorbed:how fast a technology changes theworld is not set by how fast thetechnology improves. Last stated 3 months ago 21 Jul 2026 RT Ruxandra Teslo — holds since 2026-07-21 — tap for who they are Same subject: A narrow, highly accurate model can beat a general one inside its own domain, as AlphaFold did, and materials science and chip design are next. — tap to centre the map on it A narrow, highly accurate model canbeat a general one inside its owndomain, as AlphaFold did, andmaterials science and chip designare next. Last stated 3 months ago 30 Jul 2026 JD Jeff Dean — holds since 2026-07-30 — tap for who they are Same subject: Accurate computational approaches are needed to close the protein structural coverage gap and enable large-scale structural bioinformatics. — tap to centre the map on it Accurate computational approachesare needed to close the proteinstructural coverage gap and enablelarge-scale structuralbioinformatics. Last stated 5 years ago 15 Jul 2021 DH Demis Hassabis — holds since 2021-07-15 — tap for who they are Same subject: AI models can be more accurate than physical experiments by averaging out noise, incorporating priors from large datasets, and interpolating between data points. — tap to centre the map on it AI models can be more accurate thanphysical experiments by averagingout noise, incorporating priors fromlarge datasets, and interpolatingbetween data points. Last stated 11 months ago 23 Nov 2025 EH Elliot Hershberg — holds since 2025-11-23 — tap for who they are
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At the centre A large national research cohort must transition from a pull model to a push model of medical research to achieve desired scale and cost. Last stated by 14 Feb 2015 · 12 years ago Holds Matt Might Read this korrent →