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The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule.

Drawn from what Ruxandra Teslo and Alex Telford said

design

design How things should be made and judged: what makes a design good, who should do the designing, and what an interface is for.

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What they actually said

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  1. Ruxandra Teslo That is mostly in the realm of chemistry and is intrinsically far more tractable and predictable; given a validated target, good teams usually reach a decent molecule. writingruxandrabio.com

    Geneticist by training and writer on science

    That is mostly in the realm of chemistry and is intrinsically far more tractable and predictable; given a validated target, good teams usually reach a decent molecule.
  2. Alex Telford The most significant factor preventing us from taking better molecules into clinical trials is not our ability to design arbitrary molecules, but our (lack of) understanding of underlying disease biology. In other words, we often know how to make something, but not what to make. atelfo.github.io

    Writer on biotechnology and the economics of drug development

    The most significant factor preventing us from taking better molecules into clinical trials is not our ability to design arbitrary molecules, but our (lack of) understanding of underlying disease biology. In other words, we often know how to make something, but not what to make.

Added to korrents 23 Dec 2023 · How quotes work · Something wrong? Tell us

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