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Pharmaceutical R&D productivity has fallen for decades: far more money spent per drug, with no matching improvement in the odds a candidate reaches the market.

Drawn from what Ruxandra Teslo and Alex Telford said

innovation
What this subject means

innovation Where new things come from and how they spread: invention against diffusion, and being near the factory floor.

What they actually said

  1. Ruxandra Teslo Geneticist by training and writer on science Take Eroom’s Law: the number of new drugs approved per dollar of R&D has fallen for decades, even as our scientific tools have grown vastly more powerful, the exact opposite of what the existence of more raw capability would predict. Intelligence is not the main bottleneckwritingruxandrabio.com · 21 Jul 2026All 6 korrents from this piece
    Take Eroom’s Law: the number of new drugs approved per dollar of R&D has fallen for decades, even as our scientific tools have grown vastly more powerful, the exact opposite of what the existence of more raw capability would predict.
  2. Alex Telford Writer on biotechnology and the economics of drug development The cost to discover and develop a drug today is orders of magnitude higher than in the 1950s. Despite this, the probability that a drug entering clinical trials will eventually reach the market has hardly improved in the intervening years. The pharma industry from Paul Janssen to today: why drugs got harder to develop and what we can do about itatelfo.github.io · 23 Dec 2023All 9 korrents from this piece
    The cost to discover and develop a drug today is orders of magnitude higher than in the 1950s. Despite this, the probability that a drug entering clinical trials will eventually reach the market has hardly improved in the intervening years.

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