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← A clinical trial is not only a test of a drug: early trials are…
14 connected korrents · 12 moments from 2 Oct 2013 to 4 Oct 2026.
Everything filed under Psychotherapy
Psychotherapy
Everything filed under simplicity
simplicity
Everything filed under taste
taste
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design
Everything filed under AI and science
AI and science Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Read this korrent: A clinical trial is not only a test of a drug: early trials are experiments whose real product is the human biology data everything downstream is built on. A clinical trial is not only a test of a drug: early trials are experiments whose real product is the human biology data everything downstream is built on. Last stated 8 months ago
28 Feb 2026
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. — tap to centre the map on it The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. Last stated 3 months ago
21 Jul 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-07-21 — tap for who they are
Same subject: Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. — tap to centre the map on it Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. Last stated 8 months ago
28 Feb 2026
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: How long a trial takes decides which diseases get drugs at all, because capital flows to the indications whose endpoints can be measured quickly. — tap to centre the map on it How long a trial takes decides which diseases get drugs at all, because capital flows to the indications whose endpoints can be measured quickly. Last stated 8 months ago
28 Feb 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: No amount of animal testing can guarantee a drug is safe in humans, so human volunteers must carry some irreducible risk for medicine to advance. — tap to centre the map on it No amount of animal testing can guarantee a drug is safe in humans, so human volunteers must carry some irreducible risk for medicine to advance. Last stated 3 years ago
23 Dec 2023
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
Same subject: The human data an AI model would need to predict trial outcomes can only come from trials in people, so the loop runs no faster than the trials themselves. — tap to centre the map on it The human data an AI model would need to predict trial outcomes can only come from trials in people, so the loop runs no faster than the trials themselves. Last stated 8 months ago
28 Feb 2026
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: "Evidence-based therapy" is a branding term rather than a scientific one, and in practice it is a code word for "not psychodynamic". — tap to centre the map on it "Evidence-based therapy" is a branding term rather than a scientific one, and in practice it is a code word for "not psychodynamic". Last stated 13 years ago
2 Oct 2013
JS
Jonathan Shedler — holds since 2013-10-02 — tap for who they are
Same subject: A couples therapist starts by validating where people are, not by asking them to be vulnerable. — tap to centre the map on it A couples therapist starts by validating where people are, not by asking them to be vulnerable. Last stated 3 years ago
15 May 2023
SJ
Sue Johnson — holds since 2023-05-15 — tap for who they are
Same subject: A culture that emphasizes self-esteem over self-knowledge leaves people less equipped to resist doing monstrous things. — tap to centre the map on it A culture that emphasizes self-esteem over self-knowledge leaves people less equipped to resist doing monstrous things. Last stated a year ago
8 Sept 2025
GS
Guy Spier — holds since 2025-09-08 — tap for who they are
Same subject: A business is more likely to fail from taking on too much complexity than from lacking resources. — tap to centre the map on it A business is more likely to fail from taking on too much complexity than from lacking resources. Last stated 8 years ago
29 Sept 2018
TG
Tren Griffin — holds since 2018-09-29 — tap for who they are
Same subject: A business succeeds through a small number of highly effective distribution channels, not many mediocre ones. — tap to centre the map on it A business succeeds through a small number of highly effective distribution channels, not many mediocre ones. Last stated 3 years ago
17 Feb 2024
AW
Adam Wiggins — holds since 2024-02-17 — tap for who they are
Same subject: A candidate negotiating an offer should make every ask fit one line of logic. — tap to centre the map on it A candidate negotiating an offer should make every ask fit one line of logic. Last stated 2 months ago
9 Aug 2026
AW
Adam Ward — holds since 2026-08-09 — tap for who they are
Same subject: A big part of taste is delivering high levels of craft in an accessible way so that as many people as possible can experience it. — tap to centre the map on it A big part of taste is delivering high levels of craft in an accessible way so that as many people as possible can experience it. Last stated 6 months ago
21 Apr 2026
BJ
Brandon Jacoby — holds since 2026-04-21 — tap for who they are
Same subject: A company name can have different appeal to corporate buyers versus their customers. — tap to centre the map on it A company name can have different appeal to corporate buyers versus their customers. Last stated 3 weeks ago
4 Oct 2026
PG
Paul Graham — holds since 2026-10-04 — tap for who they are
Same subject: A first draft should not be graded good or bad; it is only the material that taste then gets to act on. — tap to centre the map on it A first draft should not be graded good or bad; it is only the material that taste then gets to act on. Last stated 3 months ago
6 Aug 2026
GS
George Saunders — holds since 2026-08-06 — tap for who they are