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← A clinical trial is not only a test of a drug: early trials are…
14 connected korrents · 11 moments on record from 11 Jun 2006 to 26 Jul 2026.
Everything filed under Psychotherapy
Psychotherapy
Everything filed under simplicity
simplicity
Everything filed under design
design
Everything filed under CBT
CBT Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Same subject Read this korrent: A clinical trial is not only a test of a drug: early trials are experiments whose real product is the human biology data everything downstream is built on. A clinical trial is not only a test of a drug: early trials are experiments whose real product is the human biology data everything downstream is built on. Last stated 6 months ago
28 Feb 2026
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. — tap to centre the map on it The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule. Last stated 2 months ago
21 Jul 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-07-21 — tap for who they are
Same subject: Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. — tap to centre the map on it Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is. Last stated 6 months ago
28 Feb 2026
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: How long a trial takes decides which diseases get drugs at all, because capital flows to the indications whose endpoints can be measured quickly. — tap to centre the map on it How long a trial takes decides which diseases get drugs at all, because capital flows to the indications whose endpoints can be measured quickly. Last stated 6 months ago
28 Feb 2026
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: No amount of animal testing can guarantee a drug is safe in humans, so human volunteers must carry some irreducible risk for medicine to advance. — tap to centre the map on it No amount of animal testing can guarantee a drug is safe in humans, so human volunteers must carry some irreducible risk for medicine to advance. Last stated 3 years ago
23 Dec 2023
AT
Alex Telford — holds since 2023-12-23 — tap for who they are
Same subject: The human data an AI model would need to predict trial outcomes can only come from trials in people, so the loop runs no faster than the trials themselves. — tap to centre the map on it The human data an AI model would need to predict trial outcomes can only come from trials in people, so the loop runs no faster than the trials themselves. Last stated 6 months ago
28 Feb 2026
RT
Ruxandra Teslo — holds since 2026-02-28 — tap for who they are
Same subject: "Evidence-based therapy" is a branding term rather than a scientific one, and in practice it is a code word for "not psychodynamic". — tap to centre the map on it "Evidence-based therapy" is a branding term rather than a scientific one, and in practice it is a code word for "not psychodynamic". Last stated 13 years ago
2 Oct 2013
JS
Jonathan Shedler — holds since 2013-10-02 — tap for who they are
Same subject: A prescriber cannot outsource containment to the therapy hour: the emotional and relational dynamics are part of prescribing, not an intrusion on it. — tap to centre the map on it A prescriber cannot outsource containment to the therapy hour: the emotional and relational dynamics are part of prescribing, not an intrusion on it. Last stated 2 months ago
5 Jul 2026
AA
Awais Aftab — holds since 2026-07-05 — tap for who they are
Same subject: Character is not fixed: therapy works because habitual neural pathways can re-form, sometimes within minutes. — tap to centre the map on it Character is not fixed: therapy works because habitual neural pathways can re-form, sometimes within minutes. Last stated 3 years ago
11 Aug 2023
TR
Terry Real — holds since 2023-08-11 — tap for who they are
Same subject: AI acceleration threatens 'less software': without the constraint of scarce hours, even 37signals will likely build too much. — tap to centre the map on it AI acceleration threatens 'less software': without the constraint of scarce hours, even 37signals will likely build too much. Last stated a month ago
26 Jul 2026
DH
David Heinemeier Hansson — holds since 2026-07-26 — tap for who they are
Same subject: Convergence and simplicity make for poor goals in technology; aim for clarity instead. — tap to centre the map on it Convergence and simplicity make for poor goals in technology; aim for clarity instead. Last stated 12 years ago
18 Feb 2015
FC
Frank Chimero — holds since 2015-02-18 — tap for who they are
Same subject: Savings in time feel like simplicity: when forced to wait, life seems unnecessarily complex. — tap to centre the map on it Savings in time feel like simplicity: when forced to wait, life seems unnecessarily complex. Last stated 20 years ago
11 Jun 2006
JM
John Maeda — holds since 2006-06-11 — tap for who they are
Same subject: Action comes before motivation: you do first and feel afterwards, not the other way round. — tap to centre the map on it Action comes before motivation: you do first and feel afterwards, not the other way round. Last stated 11 months ago
30 Sept 2025
LF
Lex Fridman — holds since 2025-09-30 — tap for who they are
Same subject: No research ever showed manualized CBT to be more effective than psychodynamic therapy; it was only studied more often. — tap to centre the map on it No research ever showed manualized CBT to be more effective than psychodynamic therapy; it was only studied more often. Last stated 13 years ago
2 Oct 2013
JS
Jonathan Shedler — holds since 2013-10-02 — tap for who they are
Same subject: A therapy is only shown to be more effective if it is compared against another treatment intended to help, not against a control nobody expected to work. — tap to centre the map on it A therapy is only shown to be more effective if it is compared against another treatment intended to help, not against a control nobody expected to work. Last stated 2 years ago
11 Sept 2024
SM
Scott D. Miller — holds since 2024-09-11 — tap for who they are
At the centre
A clinical trial is not only a test of a drug: early trials are experiments whose real product is the human biology data everything downstream is built on.
Holds RT Ruxandra TesloRead this korrent →
The hard part of drug discovery is knowing what to make - which target is worth drugging - not designing the molecule.
Holds AT Alex TelfordRT Ruxandra Teslo
Better drug candidates do not shorten clinical trials, because a trial's duration is set by operational and regulatory friction rather than by how good the drug is.
Holds RT Ruxandra Teslo
How long a trial takes decides which diseases get drugs at all, because capital flows to the indications whose endpoints can be measured quickly.
Holds AT Alex TelfordRT Ruxandra Teslo
No amount of animal testing can guarantee a drug is safe in humans, so human volunteers must carry some irreducible risk for medicine to advance.
Holds AT Alex Telford
The human data an AI model would need to predict trial outcomes can only come from trials in people, so the loop runs no faster than the trials themselves.
Holds RT Ruxandra Teslo
"Evidence-based therapy" is a branding term rather than a scientific one, and in practice it is a code word for "not psychodynamic".
Holds JS Jonathan Shedler
A prescriber cannot outsource containment to the therapy hour: the emotional and relational dynamics are part of prescribing, not an intrusion on it.
Holds AA Awais Aftab
Character is not fixed: therapy works because habitual neural pathways can re-form, sometimes within minutes.
Holds TR Terry Real
AI acceleration threatens 'less software': without the constraint of scarce hours, even 37signals will likely build too much.
Holds
Convergence and simplicity make for poor goals in technology; aim for clarity instead.
Holds FC Frank Chimero
Savings in time feel like simplicity: when forced to wait, life seems unnecessarily complex.
Holds JM John Maeda
Action comes before motivation: you do first and feel afterwards, not the other way round.
Holds LF Lex Fridman
No research ever showed manualized CBT to be more effective than psychodynamic therapy; it was only studied more often.
Holds JS Jonathan Shedler
A therapy is only shown to be more effective if it is compared against another treatment intended to help, not against a control nobody expected to work.
Holds SM Scott D. Miller