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Jacob Trefethen

What Jacob Trefethen thinks about epidemiology

@jacob-trefethen · 14 positions · On ppll ↗

Head of global health R&D at Open Philanthropy, where he directs funding for vaccines, drugs and diagnostics aimed at diseases that get little commercial attention. He writes at blog.jacobtrefethen.com and co-hosts the Hard Drugs podcast with Saloni Dattani.

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2 dated positions, 2025, in their own words. Our reading of what Jacob Trefethen has said — not written or endorsed by them.

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  1. Measles is technologically “solved”, but not everyone trusts the solutions or their messengers.

    ↗AI will not suddenly lead to an Alzheimer's cureblog.jacobtrefethen.com 5th of 5 in this piece

  2. 2 months earlier
  3. Infectious diseases as a category receive vastly less R&D spending from industry than non-communicable diseases, per death they cause, because they disproportionately kill people in lower- and middle-income countries where the payoff for making a cure is less lucrative.

    ↗A Quantitative Approach to Vaccine Fundingblog.jacobtrefethen.com 2nd of 2 in this piece