5 korrents from this piece
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Their wordsThe current success rate for a drug entering clinical trials is only about ten percent, meaning 90 percent of all drugs fail.
Their wordsEven if AI can help design more effective drugs, timelines will not compress until we solve the operational and regulatory bottlenecks of trials.
Their wordsTrials serve two distinct functions: validation — confirming whether a drug works and is safe — and learning, or generating biological data to refine our understanding of a disease, a compound, and the relationship between the two.
Their wordsLastly, the duration of a clinical trial does not merely determine how fast an individual therapy reaches patients. It also shapes which diseases attract serious investment and which do not.
Their wordsBut remember that such data can only come from trials in people (mice are nice, but most animal results simply do not translate.)