Ten billion dollars over ten years would deliver most of a list of missing life-saving health technologies, so their absence is a funding choice rather than a scientific limit.

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• AI will not on its own compress decades of medical progress into a few years, because the binding constraint is human data, clinical trials and regulation rather than intelligence. JTJacob Trefethen2 Aug 2025
• R&D spending varies more than tenfold across diseases for no good reason, which is where the best opportunities in science funding are. JTJacob Trefethen29 May 2025
• Not every bottleneck on medical progress is one AI can remove, and which ones will remain can be guessed at now. JTJacob Trefethen2 Aug 2025
• The pace of medical innovation can be sped up or slowed down by policy, funding and institutional choices. SDSaloni Dattani28 Dec 2025
• Some ideas are worth funding with fifty million dollars or with nothing, and never with five million, because underfunding buys you an ambiguous outcome instead of an answer. MHMax Hodak7 Aug 2026

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