Health optimisation has overshot: minimising a measured risk is not worth it if the cost is not having lived.

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  Measurable, modifiable biological age at the organ and cell level is the most important advance yet in the science of human ageing.

  Topol calls measurable, modifiable biological age at the organ and cell level the most important advance yet in the field. Hansson says health optimisation has overshot, and that minimising a measured risk is not worth it if the cost is not having lived. A better measurement is exactly what makes the optimisation Hansson is warning about possible.

Shared subject first, then similar wording. They may agree or disagree.

• Risk can be reduced without reducing returns by structuring bets in a more diversified way. RDRay Dalio27 Sept 2022
• Non-risk-adjusted mortality data cannot support patient choice and only signal that a fuller review is required. DSDavid Spiegelhalter19 Aug 2004
• The deeper anyone digs into a charity's cost-effectiveness estimate, the more unwarranted optimism they find, so the right prior on giving is a sceptical one. HKHolden Karnofsky18 Aug 2011
• Moving money out of global health and into existential risk is a gamble paid for with lives that could have been saved now. MJMatt Johnson21 Dec 2023
• At a market price-earnings ratio of twenty-three there is little upside and a long way to fall, where at fifteen there would be much less risk. JDJamie Dimon16 Jul 2025

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