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Lior Pachter

Lior Pachter

@lior-pachter · 9 positions

Computational biologist; Bren Professor of Computational Biology at Caltech. Known for RNA-seq and single-cell analysis methods such as kallisto. Writes the Bits of DNA blog on genomics, statistics, research integrity and mathematics.

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  1. AI alignment

    The goals of the AI companies and the goals of the mathematical community are severely misaligned

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com 1st of 3 in this piece

  2. mathematics

    Of course every mathematician knows that the mathematics community does not nurture with great care all of its students and ideas.

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com 2nd of 3 in this piece

  3. mathematics

    AI companies and mathematicians should instead be asking what both ought to be aligned to: understanding, attribution, intellectual generosity, and the nurturing of students and ideas, and not merely the production or recognition of results.

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com 3rd of 3 in this piece

  4. 7 months earlier
  5. The empowerment of the majority with accelerants may serve to massively amplify flawed approaches, making it much harder for the minority opinion to prevail, even if it is correct.

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com 1st of 2 in this piece

  6. I don't believe that current publication systems, whether for preprints, conference proceedings, or journals, can withstand the onslaught of work that is already in progress, let alone the amount of material that is to come.

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com 2nd of 2 in this piece

  7. 3 months earlier
  8. The Banbury Center was founded as an old boys club. Meetings are invitation only, with invites by the old boys for other old boys.

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com

  9. 5 months earlier
  10. mathematics

    In regards to erroneous proofs of true statements in mathematics, I doubt they are common and disagree with Litt that they constitute a "not insubstantial portion of the literature".

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com 1st of 3 in this piece

  11. In other words, most published research results are true and replete with correct proofs and/or evidence of their truth.

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com 2nd of 3 in this piece

  12. However, even when published results are wrong, they usually turn out to be useful.

    ↗Reviews and commentary on computational biology by Lior Pachterliorpachter.wordpress.com 3rd of 3 in this piece