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Eric Topol

Eric Topol

@eric-topol · 9 positions · On ppll ↗

Cardiologist, founder and director of the Scripps Research Translational Institute, and author of Super Agers. Writes Ground Truths, a free newsletter reviewing new medical research.

Eric Topol did not write this page.

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2 of Eric Topol's claims fit 1 mental models. Most often: The map is not the territory.

Models we see in what they say

Our reading: their claim applies the idea without naming it. The claim is theirs; filing it here is ours.

The map is not the territory

Every model, word or plan is a simplified map of reality; useful when its structure matches, misleading when mistaken for the thing itself.

Used by 56 others

A coronary calcium score of zero does not mean the arteries are free of disease, and in a younger adult it is far weaker reassurance than it looks.

  1. Eric Topol Cardiologist, founder and director of the Scripps Research… We know that arteries with a calcium (CAC) score of zero can be highly inflamed, and that high CAC scores are not necessarily high-risk for cardiovascular events. The Coronary Artery Inflammation Controversyerictopol.substack.com · 5 Sept 2026All korrents from this piece
    Their wordsWe know that arteries with a calcium (CAC) score of zero can be highly inflamed, and that high CAC scores are not necessarily high-risk for cardiovascular events.

    ↗The Coronary Artery Inflammation Controversyerictopol.substack.com

    5 Sept 2026

A drug that moves a surrogate blood marker in the right direction cannot be assumed to prevent heart attacks and strokes.

  1. Eric Topol Cardiologist, founder and director of the Scripps Research… We can’t count on surrogate blood markers to guide the results of cardiovascular clinical outcome trials. The Coronary Artery Inflammation Controversyerictopol.substack.com · 5 Sept 2026All korrents from this piece
    Their wordsWe can’t count on surrogate blood markers to guide the results of cardiovascular clinical outcome trials.

    ↗The Coronary Artery Inflammation Controversyerictopol.substack.com

    5 Sept 2026