Rust's least mature area is the front end: write the backend in Rust and the front end in TypeScript rather than shipping Rust to the browser through WebAssembly.

My opinion is that the least mature area is front end. There have been some attempts to compile Rust to Web Assembly and then run it on the web as a front end as a replacement for TypeScript. But if I was writing a web server, I would totally use Rust for the back end and TypeScript for the front end. I would not really go the web assembly route.