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Vinay Prasad’s Observations and Thoughts

Vinay Prasad · 9 Oct 2026

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Every claim below was made in this piece, quoted word for word and numbered in the order the piece makes them, so you can read it there rather than take our word for it. The sentence above each quote is our reading of the claim, not their wording. Each quote was checked against a stored copy of the page at build time; where the two differ, the quote is the fact.

  1. Many trials meant to inform the US practice are unethical because the control arm is something we have not done in the US for quite some time- a standard that was already beaten.
  2. These are people who believe that they know what works based on mechanistic science and low quality observational studies.
  3. Such a randomized study would be imminently important in the United States, where this issue is heavily debated, and neither side has gold standard evidence, but the zealotry side uses bizarre arguments.

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