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The POET II trial authors chose their primary and secondary endpoints incorrectly.
Drawn from what John Mandrola said
What John Mandrola actually said
- John Mandrola Cardiac electrophysiologist in Louisville, Kentucky
My issue is the author's choice of primary and secondary endpoints. A rule of evidence is that you choose as the primary endpoint the most important outcome. Secondary outcomes are chosen to bolster or support the primary. POET II authors got this backward; but readers of the trial can still make conclusions from the evidence-it's just different from what the authors conclude.
Where this was said
↗Sensible Medicinesensible-med.com
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