Hub-and-Spoke Biotechs: BridgeBio

Elliot Hershberg · 16 Feb 2025

The piece opens with

The biotech industry has not undergone the same exhaustive search for every commercializable opportunity that followed the internet's growth boom.

Their wordsWhat we haven't seen is the same type of frantic hunt for every nugget of value that could be commercialized as a result of this enormous secular trend.

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Our reading
The biotech industry has not undergone the same exhaustive search for every commercializable opportunity that followed the internet's growth boom.

Their wordsWhat we haven't seen is the same type of frantic hunt for every nugget of value that could be commercialized as a result of this enormous secular trend.
Our reading
The number of diseases with a known molecular explanation has grown far faster than the number of new drugs developed to treat them.

Their wordsThe set of diseases for which we have a molecular explanation-which resembles the equivalent of the Craigslist homepage for this analogy-has grown far faster than the corresponding set of new drugs to treat them.
Our reading
The Human Genome Project's results have been less transformative than initially advertised relative to its cost.

Their wordsI think this partially explains some of the discontent in the scientific community about the Human Genome Project. After billions of dollars that could have been spent in other places, the result is less transformative than initially advertised.

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